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Curriculum Vitae                   Edward I. Shaw, Ph.D.                               August,  2006

Personal Information

Education and Training

Professional Qualifications

Personal Information:

CURRENT POSITION TITLE:

                Assistant Professor

                Department of Microbiology and Molecular Genetics

                College of Arts and Sciences

Oklahoma State University

PROFESSIONAL ADDRESS:

                Department of Microbiology and Molecular Genetics

Oklahoma State University

                307 Life Sciences East

Stillwater, OK 74078

                Phone: (405) 744-7180

                Fax:     (405) 744-6790

HOME ADDRESS:

                5601 W. 68th Street

Stillwater, OK 74074

                Phone: (405) 372-1701

Education and Training:

POST DOCTORAL TRAINING:

                Intramural Research Training Award

                Laboratory of Intracellular Parasites, Rocky Mountain Laboratories

                National Institute of Allergy and Infectious Diseases, National Institutes of Health

                Hamilton, MT. 1997-2000

                Advisor - Ted Hackstadt, Ph.D.

GRADUATE EDUCATION:

                Ph.D., University of South Alabama College of Medicine, Mobile, AL.

                Department of Microbiology and Immunology, 1990-1997.

                Graduate Advisor - David O. Wood, Ph.D.

UNDERGRADUATE EDUCATION:

                B.S., Georgia Southwestern College, Americus, Georgia.

                Major, Biology; Minor, Chemistry (B.A. equivalent), 1984-1989.

ACADEMIC HONORS:

                Alumni Scholarship, Georgia Southwestern College (1984)

                Who’s Who in American Universities and Colleges (1988-89)

                Gamma Beta Phi Honor Society, Georgia Southwestern College (1986-89)

                Blue Key Honor Fraternity, Georgia Southwestern College (1986-89)

GRADUATE AWARDS:

                University of South Alabama Graduate College Travel Award (1996)

                American Society for Microbiology Student Travel Grant (1996)

Professional Qualifications:

PROFESSIONAL POSITIONS:

                Assistant Professor

                Department of Microbiology and Molecular Genetics

                College of Arts and Sciences

Oklahoma State University

Stillwater, OK. 2005-present

                Adjunct Assistant Professor

                Department of Veterinary Pathobiology

                Center for Veterinary Health Sciences

Oklahoma State University

Stillwater, OK. 2006-present

                Senior Service Fellow, Microbiologist

                Coxiella Unit, Rickettsiology Section

                Viral and Rickettsial Zoonoses Branch

                DVRD, NCID, CDC. Atlanta, GA. 2000-2004                   

TRAINING AND MENTORING POSITIONS:

                Graduate Mentor for PhD Student – Saugata Mahapatra, Dec. 2005-present          

                Graduate Mentor for PhD Student – Kent Morgan, Feb. 2005-present

                Adjunct member of Ph.D. committee, West Virginia Univ. (2002-2004) - Jeffrey Miller

                Co-mentor for CDC ORISE Fellow (2001 – 2002) – Brendan Lucey

                Co-mentor for CDC ORISE Fellow (2002 – 2004) – Rachael Priestly

                Co-mentor for CDC Summer Fellow (2002) – Karen Stewart

                NABS & 4990 Mentor for undergraduate student – Ryan Trojan, September 2005-present

                4990 Mentor for undergraduate student – Sarah Davidson, September 2006-present

                4990 Mentor for undergraduate student – Shawn Shelton, September 2005-May 2006

                Mentor to undergraduate lab assistant – Rebecca Pace, September-December 2005

PROFESSIONAL SOCIETY MEMBERSHIPS:

                American Society for Microbiology

                American Society for Rickettsiology and Rickettsial Diseases

                American Society for Cell Biology

TEACHING EXPERIENCE:

                Recent Advances in Microbiology, Oklahoma State University, Spring 2005.

                Microbiology Laboratory Assistant, Georgia Southwestern College, Spring 1989.

                Medical Microbiology Laboratory, USA College of Medicine, Fall 1992.

                Biomedical Enrichment And Recruitment Lecturer, Summers 1992-96.

                Guest Lecturer, Department of Microbiology Immunology and Cell Biology

Robert C. Byrd Health Sciences Center, West Virginia University, Fall 2004

                (Medical Microbiology –Zoonotic and Vector Borne Disease Lectures)

                Contributing Instructor – MICR5153 (Emerging Infectious Agents).

                Three hours of lecture including Zoonotic Diseases, Culling and Quarantine, and Molecular Approaches to Diagnostics and Detection.

                Contributed test questions and graded pertinent sections of exam 1. Spring 2006.

                Contributing Instructor – VBSC5553 (Bacterial Pathogenesis).

                Three hours of lecture covering the topic of Cell Invasion and Intracellular Parasitism.

                Contributed test questions and graded pertinent sections of exam 2. Spring 2006.

                Instructor - BIOL1114 (General Biology) - Spring 06 – Three hours of lecture/week. 168 students. Spring 2006.

PUBLICATIONS:

Young, Carrie L., Barr, J.R., Woolfitt, A. R., Moura, H., Shaw, E. I., Thompson, H. A., and Fernandez, F. M.. Coxiella burnetii Strain Identification by Partial Least Squares-Discriminant Analysis of MALDI-TOF MS Biomarker Fingerprints. Analytica Chimica Acta, (in press).

McQuiston, J. H., Nargund, V., Miller, J. D., Priestley, R., Shaw, E. I., and Thompson, H. A.. Prevalence of Antibodies to Coxiella burnetii among Veterinary School Dairy Herds in the United States, 2003. Vector-Borne and Zoonotic Diseases, (2005) Spring 5(1), 90-91.

Shaw, Edward I., Moura, H., Woolfitt, A. R., Ospina, M., Thompson, H. A., and Barr, J. R.. Identification of Biomarkers of Whole Coxiella burnetii Phase I by MALDI-TOF Mass Spectrometry. Analytical Chemistry. (2004) July 15; 76(14), 4017-4022.

Thompson, Herbert A., Hoover, T. A., Vodkin, M. H., and Shaw, E. I.. Do Chromosomal Deletions in the Lipopolysaccharide Biosynthetic Regions Explain All Cases of Phase Variation in Coxiella burnetii Strains? An Update. In Rickettsiology: Present and Future Directions. Annals of the New York Academy of Science. (2003) Vol. 990. pg 664-670.

Shaw, Edward I., Dooley, C. A., Fischer, E. R., Scidmore-Carlson, M. A., Fields, K. A.,and Hackstadt, T.. Three temporal classes of gene expression during the Chlamydia trachomatis developmental cycle. Mol. Micro. (2000) 37(4), 913-925.

Hackstadt, Ted, Scidmore-Carlson, M. A., Shaw, E. I., and Fischer, E. R. The Chlamydia trachomatis IncA protein is required for homotypic vesicle fusion. Cell. Micro. 1 (1999) 119-130.

Scidmore-Carlson, Marci A., E. I. Shaw, C. A. Dooley, E. R. Fischer, and T. Hackstadt. Identification and characterization of a Chlamydia trachomatis early operon encoding four novel inclusion membrane proteins. Mol. Micro. (1999) Aug; 33(4): pg 753-765.

Shaw, Edward I., Scidmore-Carlson, M. A., and Hackstadt, T. 1998.Temporal Expression of Chlamydia trachomatis Transcripts from Putative Membrane Spanning Protein Genes. Chlamydial Infections: Proceedings of the Ninth International Symposium on Human Chlamydial Infection. Napa, CA. pg 559-562.

Scidmore-Carlson, M., Shaw, E.I., Dooley, C.A., and Hackstadt, T. 1998 Identification and Characterization of Putative Chlamydia trachomatis Inclusion Membrane Proteins. Chlamydial Infections: Proceedings of the Ninth International Symposium on Human Chlamydial Infection. Napa, CA. pg 103-106.

Waite, Rebecca T., Shaw, E. I., Winkler, H. H., and Wood, D. O.. Isolation and characterization of the dnaA gene of Rickettsia prowazekii. Acta Virol. 42(2), (1997) 95-101.

Shaw, Edward I., Marks, G. L., Winkler, H. H., and Wood, D. O.. Transcriptional Characterization of the Rickettsia prowazekii Major Molecular Synthesis Operon. J. Bacteriol. 179 (1997) 6448-6452.

Foster, John W., Park, Y. K., Bang, I. S., Karem, K., Betts, H., Hall, H. K. and Shaw, E. I.  Regulatory Circuits Involved with pH-Regulated Gene Expression in Salmonella typhimurium. Microbiology. 104 (1994) 341-352.

Shaw, Edward I. and Wood, D. O. Characterization of a Rickettsia rickettsii DNA Fragment Analogous to the firA-ORF-lpxA Region of Escherichia coli. Gene. 140 (1994) 109-113.

Elder, Elizabeth D., Scott, J. B., Reid, J. C., and Shaw, E. I.  Utilization of Organic N-Halamine Disinfectants Against Legionella Pneumophila. Georgia J. Of Science. 51, 4 (1993) 173-182.

ABSTRACTS:

Ryan Trojan, Shawn Shelton, Christopher Cuff, and Edward I. Shaw. 2006. Expression of Genes Unique to the QpH1 Plasmid of Coxiella burnetii During Infection of Host Cells. 20th Meeting of The American Society for Rickettsiology. September 2-7. Pacific Grove, CA.

Robert Massung, Carrie L. Young-Pierce, John Barr, Adrian R. Woolfitt, Hercules Moura, Rachael A. Priestley, Edward I. Shaw, Herbert A. Thompson, and Facundo M. Fernandez. Mass Spectrometry for the Detection and Differentiation of Coxiella burnetii Isolates. 20th Meeting of The American Society for Rickettsiology. September 2-7. Pacific Grove, CA.

Ryan Trojan, Shawn Shelton, Christopher Cuff, and Edward I. Shaw. 2006. Expression of Genes Unique to the QpH1 Plasmid of Coxiella burnetii During Infection of Host Cells. 106th American Society for Microbiology, General Meeting. May 21-26. Orlando, Fl.

Adrian R. Woolfitt, Carrie L. Young, Hercules Moura, Barun K. De Patty P. Wilkins, Herbert A. Thompson, Edward I. Shaw, Antonis Pavlopoulos, Maria I. Solano & John R. Barr. March 26 - 30, 2006. “Identification of Bacillus anthracis and Coxiella burnetii by MALDI-TOF MS protein fingerprinting and LC-ESI/MS/MS proteomic approaches”. American Chemical Society Meeting & Exposition. Atlanta, GA USA.

Carrie L. Young, Adrian R. Woolfitt, Hercules Moura, Barun K. De, Patty P. Wilkins, Edward I. Shaw, Herbert A. Thompson, Antonis Pavlopoulos, Facundo M.  Fernandez, John R. Barr. March 26 - 30, 2006.  “Bacillus anthracis and Coxiella burnetii Classification on Biomarker Latent Variables via MALDI MS”. American Chemical Society Meeting & Exposition. Atlanta, GA USA.

Carrie L. Young, J. R. Barr, A. R. Woolfitt, H. Moura, E I. Shaw, H. A. Thompson, and F. M.  Fernandez. January 29, 2005. “Coxiella burnetii Strain Identification by Partial Least Squares-Discriminant Analysis of MALDI-TOF MS Biomarker Fingerprints”.  17th Sanibel Island Mass Spectrometry in Forensic Science and Counterterrorism Meeting of the American Society for Mass Spectrometry (ASMS). Sanibel Island, FL.

E. I. Shaw and H. A. Thompson. 2004. RNA Expression of the Coxiella burnetii Type IV Secretion System Region I During the Course of Infection. 104ADVANCE \u 3thADVANCE \d 3 Annual Meeting of the American Society for Microbiology. New Orleans, LA.

E. I. Shaw, H. Moura, A.R. Woolfitt, A. Pavlopoulos, H.A. Thompson and J.R. Barr. 2004. Mass Spectrometry Detection and Identification of ScvA, a general Biomarker that is Common to Virulent and Avirulent Coxiella burnetii Isolates. International Conference of Imerging Infectious Diseases. Atlanta, GA.

E. I. Shaw, H. Moura, A. R. Woolfitt, M. Ospina, H. A. Thompson, and J. R. Barr. 2003. Identification of Biomarkers of Whole Coxiella burnetii Phase I by MALDI-TOF Mass Spectrometry. Sesqui-Annual meeting of the American Society for Rickettsiology and Rickettsial Diseases, Rocky Gap, Maryland.

H. A. Thompson, R. Priestley, E. I. Shaw, J. McQuiston, B. Lucey, K. Stewart, J.D. Miller, and G. Dasch. 2003. Taqman PCR Studies Detecting Coxiella burnetii  in Veterinary, Mock Clinical, and Environmental Samples. Sesqui-Annual meeting of the American Society for Rickettsiology and Rickettsial Diseases, Rocky Gap, Maryland.

J.H. McQuiston, E. Shaw, R. Priestley, J. Miller, J.E. Childs, and H.A. Thompson. 2003.

Q fever Surveillance in the United States: Epidemiology and Geographic Trends in Humans and Animals. Sesqui-Annual meeting of the American Society for Rickettsiology and Rickettsial Diseases, Rocky Gap, Maryland.

J.D. Miller, E.I. Shaw, and H.A. Thompson. 2003. Characterization of the Coxiella burnetii Nine Mile CTP synthetase. Sesqui-Annual meeting of the American Society for Rickettsiology and Rickettsial Diseases, Rocky Gap, Maryland.

Shaw, Edward I., Moura, Hercules, Woolfitt, Adrian R., Ospina, M., Thompson, Herbert A., and Barr, John R.. 2003. Detection of Biomarkers of Whole Coxiella burnetii phase I by MALDI-TOF Mass Spectrometry. ASM Biodefense Research Meeting. Baltimore, MD.

Thompson, Herbert A., Hoover, Timothy A., Vodkin, Michael H., and Shaw, Edward I.. 2002. Do Chromosomal Deletions in the Lipopolysaccharide Biosynthetic Regions Explain All Cases of Phase Variation in Coxiella burnetii Strains? An Update. International Conference on Rickettsiae and Rickettsial Diseases. Ljubljana, Slovania.

Lucey, Brendan, Shaw, Edward I., Thompson, Herbert A., Miller, Jeffrey D., and Dasch, Gregory A. 2002. Use of Real-Time PCR to Detect Coxiella burnetii in Clinical and Veterinary Samples. International Conference on Rickettsiae and Rickettsial Diseases. Ljubljana, Slovania.

Shaw, Edward I., Dooley, Cheryl A., Scidmore-Carlson, Marci A., and Hackstadt, Ted. 1999. Temporal Gene Expression in the Chlamydia trachomatis Developmental Cycle. 39ADVANCE \u 3thADVANCE \d 3 Annual Meeting of the American Society for Cell Biology. Washington, DC.

Scidmore-Carlson, Marci A., Shaw, Edward I., and Hackstadt, Ted. 1998. Identification of Three Novel Chlamydia trachomatis Inclusion Membrane Proteins. 38ADVANCE \u 3thADVANCE \d 3 Annual Meeting of the American Society for Cell Biology. San Fransico, CA.

Shaw, Edward I., Scidmore-Carlson, Marci A., and Hackstadt, Ted. 1998. Temporal Transcript Expression from Chlamydia trachomatis Inclusion Membrane Protein Genes. 38ADVANCE \u 3thADVANCE \d 3 Annual Meeting of the American Society for Cell Biology. San Fransico, CA.

Shaw, Edward I., Scidmore-Carlson, Marci A., and Hackstadt, Ted. 1998. Temporal Expression of Chlamydia trachomatis Transcripts from Putative Membrane Spanning Protein Genes. 98ADVANCE \u 3thADVANCE \d 3 Annual Meeting of the American Society for Microbiology. Atlanta, GA.

Shaw, Edward I., Marks, G. Lynn, Winkler, Herbert H. and Wood, David O. 1996. Transcriptional Characterization of the Rickettsia prowazekii Major Macromolecular Synthesis Operon Analog. 96ADVANCE \u 3thADVANCE \d 3 Annual Meeting of the American Society for Microbiology. New Orleans, LA. pg 224.

Elder, Elizabeth D., Shaw, Edward I., and Jones, John F. 1989. Imidazolidinones as Alternative Water Disinfectants. 89ADVANCE \u 3thADVANCE \d 3 Annual Meeting of the American Society for Microbiology. New Orleans, LA. pg 293.

MEETING PRESENTATIONS:

Shaw, Edward I., and Thompson, H. A. 2003. The Expression of Select Type IV Secretion Homologs in Coxiella burnetii. Sesqui-Annual meeting of the American Society for Rickettsiology and Rickettsial Diseases, Rocky Gap, Maryland.

Shaw, Edward I., Winkler, Herbert H. and Wood, David O. 1997. Differential Transcription Within the Rickettsia prowazekii rpoD Gene Linkage Group. Sesqui-Annual meeting of the American Society for Rickettsiology and Rickettsial Diseases, Seven Springs, Pennsylvania.

Shaw, Edward I., Marks, G. Lynn, Winkler, Herbert H. and Wood, David O. 1996. Analysis of Rickettsia prowazekii Major Macromolecular Synthesis Operon Transcripts. Sesqui-Annual meeting of the American Society for Rickettsiology and Rickettsial Diseases, Pacific Grove , California.

Shaw, Edward I., Wood, David O. and Anderson, Burt. 1992. Identification of Rickettsia rickettsii Genes involved in Lipid A Biosynthesis. Sesqui-Annual meeting of the American Society for Rickettsiology and Rickettsial Diseases, Hamilton, Montana.

BOOK CHAPTERS:

Miller, J. D., E. I. Shaw, H. A. Thompson.  Coxiella burnetii, Q fever, and Bioterrorism. In: Microbial Infection and Bioterrorism. B. Anderson, H. Friedman, M. Bendinelli, Eds. January 2006